Research Article
Published: 02 July, 2024 | Volume 8 - Issue 1 | Pages: 033-037
We reviewed our outcomes of patients with relapsed/refractory Hodgkin Lymphoma treated with autologous stem cell transplant over a 30-year period, 1992 to 2022 and are reporting 15-year Disease-Free Survival (DFS) and Overall Survival (OS) of the 36 patients treated (19 men, 17 women, median age 41). Over the years there were different preparative regimens employed (carmustine, etoposide, melphalan and BCNU, etoposide, cytarabine, and melphalan) as well as post-transplant consolidation therapy (brentuximab). With a median follow-up of 15 years, the DFS is 52% and OS is 64%. Long-term complications include cardiomyopathy and second malignancies.
The use of better salvage regimens and post-transplant consolidation therapy should lead to better outcomes.
Read Full Article HTML DOI: 10.29328/journal.jsctt.1001040 Cite this Article Read Full Article PDF
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