Abstract

Opinion

The complement cascade as a target against SARS-CoV-2-induced pneumonia

Gianluigi Ferretti*

Published: 14 February, 2023 | Volume 7 - Issue 1 | Pages: 001-002

Fox, et al. [1] reported on the relevant cardiopulmonary findings in a series of autopsies of patients deceased from SARS-CoV-2 infection. In particular, regarding the histologic examination of the lungs, they observed bilateral diffuse alveolar damage with a lymphocytic infiltrate, thickened alveolar capillaries, fibrin thrombi within the capillaries and small vessels, and entrapment of neutrophils, without any significant neutrophilic, infiltrate within airways or the interstitium. 

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001029 Cite this Article Read Full Article PDF

References

  1. Fox SE, Akmatbekov A, Harbert JL, Li G, Brown JQ, Vander Heide RS. Pulmonary and Cardiac Pathology in Covid-19: The First Autopsy Series from New Orleans. MedRxiv Preprint. doi:https://doi.org/10.1101/2020.04.06.20050575
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