Abstract

Short Communication

Stem cells in heart failure some considerations

Federico Benetti*, Natalia Scialacomo and Bruno Benetti

Published: 25 January, 2018 | Volume 2 - Issue 1 | Pages: 001-003

Stem cell treatments depend not only on the type of cell to be used but also on the different implantation techniques. Intravascular cell injections are known to rapidly separate from the vessels. On the other hand, it is also well known that direct injection into the myocardium provides better coupling within the heart muscle. That were the cases of Embriofetal stem cell (HFDSC) or Autologous stem cells (ABMSC) in our experience focused on direct approaches.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001009 Cite this Article Read Full Article PDF

Keywords:

Heart failure; Stem cells; Autologous stem cells; Embriofetal stem cell

References

  1. Meerson FZ. The myocardium in hiperfunction, hipertrophy and heart failure. Circ Reserch. 1969; 25: 1-163. Ref.: https://goo.gl/ZWF8iV
  2. Zak R. Cardiac hipertrophy: biochemical and cellular relationships. Hosp Pract (Off Ed). 1983; 18: 85-97. Ref.: https://goo.gl/AVUL1h
  3. Prosper F, Pérez A, Merino J, Gregorio R, Chachques JC, et al. Adult stem cells for myocardial repair. Basic Appl Myol. 2003; 13: 15-22. Ref.: https://goo.gl/yJtHWQ
  4. Colucci WS, Braunwald E. Patophisiology of heart failure in Braunwald¨s Heart Disease 5th edition Saunders company 1997.
  5. Prokop D. Marrow Stromal cells as Stem Cells for nonhematopoietic tissues. Science. 1997; 276: 71-76. Ref.: https://goo.gl/JfAJZv
  6. Pittenger MF, Makay A, Beck SC, Jaiswal RK, Douglas R, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999; 284: 143-147. Ref.: https://goo.gl/mzszL2
  7. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, et al. Cardiomyocites can be generated from marrow stromal cells in vitro. J Clin Invest. 1999; 105: 697-705. Ref.: https://goo.gl/8F6TX2
  8. Xu M, Wani M, Dai YS, Wang J, Yan M, et al. Differentiation of bone marrow stromal cells into cardiac phenotype requires intracellular communication with myocites. Circulation. 2004; 110: 2658-2665. Ref.: https://goo.gl/iiSDqg
  9. Chedrawy EG, Wang JS, Nguyen DM, Shum-Tim D, Chiu RCJ. Incorporation and integration of implanted myogenic and stem cells into native myocardial fibres: anatomic basis for functional improvements. J of Thoracic and Cardiovascular Surgery. 2002; 124: 584-590. Ref.: https://goo.gl/nyJhHB
  10. Pittenger MF, Bradley JM. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res. 2004; 95: 9-20. Ref.: https://goo.gl/Hcthfk
  11. Vilas-Boas F, Feitosa GS, Soares MB, Pinho-Filho JA, Mota A. Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas disease. Arq Bras Cardiol. 2004; 82: 185-187. Ref.: https://goo.gl/XoWhvY
  12. Benetti F, Viña RF, Patel AN. OPCABG plus simultaneous autologus stem cells implants TCTMD.com. 2003.
  13. Patel AN, Geffner L, Vina RF, Saslavsky J, Urschel HV, Jr. Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study. J Thoracic and Cardiovascular Surgery. 2005; 130: 1631-1638. Ref.: https://goo.gl/UayHSM
  14. Comella K, Parcero J, Bansal H, Perez J, Lopez J, et al. Effects of the intramyocardial implantation of stromal vascular fraction in patients with chronic ischemic cardiomyopathy. J Transl Med. 2016; 14: 158. Ref.: https://goo.gl/Nvzyk1
  15. Anastasiadis K, Antonitsis P, Westaby S, Reginald A, Sultan S, et al. Implantation of a Novel Allogeneic Mesenchymal Precursor Cell Type in Patients with Ischemic Cardiomyopathy Undergoing Coronary Artery Bypass Grafting: an Open Label Phase IIa Trial. Journal of Cardiovascular Translational Research. 2016; 9: 202-213. Ref.: https://goo.gl/TCPQTo
  16. Poulin MF, Deka A, Mohamedali B, Schaer GL. Clinical Benefits of Stem Cells for A Systematic Review of the Existing Data and Ongoing Trials. Cell Transplant. 2016; 25: 1911-1923. Ref.: https://goo.gl/HJs294
  17. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Chugh AR, et al. The TIME Trial-Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis. Circulation Research. 2017. Ref.: https://goo.gl/pSRHsb
  18. Benetti F, Peñherrera E, Maldonado T, Vera YD, Subramanian V, et al. Direct Myocardial Implantation of Human Fetal Stem Cells in Heart Failure Patients: Long-term Results. The Heart Surgery Forum. 2010; 13: 31-35. Ref.: https://goo.gl/gsu9jR

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More

Help ?